Do you know the difference between potassium diformate and several common feed substitutes?

 2020 is the first year of the ban on anti-antibiotics, and more feed additives that can replace antibiotics have been used. While looking for a brand-new anti-fighting solution, the role of antifighting feed additives is also the top priority of the entire feed breeding industry. Facing the dazzling array of anti-antibiotic products on the market, do you know the difference between potassium diformate and several common anti-antibiotic products?


Chinese herbal medicine

With the country's restrictions on the use of antibiotics in the past two years, Chinese herbal medicines for veterinary medicine have received greater attention. What is the feasibility of Chinese herbal medicines in replacing antibiotics?


Function: The function is relatively one-sided, and has a certain effect in immune regulation.


Effect: The effect is slow and the function is not comprehensive enough. Due to its rough processing, large amount of addition, complex formula, and unstable effect, the research progress is slow and cannot be truly replaced.


Potassium diformate

The feed additive potassium diformate is a new type of additive that can lower the pH value of feed in the digestive tract and provide animals with the most suitable digestive tract environment.


Antibacterial: It has obvious antibacterial effect.


Function: It has the growth-promoting effect of antibiotics. In fact, it uses its strong killing effect on pathogenic bacteria in the intestine. Its unique antimicrobial function is based on the comprehensive effect of formic acid and formate. Potassium is ingested and passed through the acidic stomach to reach the neutral and alkaline back intestines, which is automatically decomposed into formic acid and formate. The non-dissociated formic acid passes through the bacterial cell wall to lower the pH in the cell. , Intracellular PH is close to 7, organic acid enters the cell for one generation, destroys the enzyme action in the cell and nutrient delivery system, so that microorganisms cannot reproduce, cause death, and have antibacterial and sterilization functions; formate anion decomposes bacterial cell wall protein outside the cell wall , Play a bactericidal and antibacterial effect.


Potassium diformate is not only highly acidic, but also slowly released in the digestive tract, with high buffering capacity, which can avoid excessive fluctuations in the acidity of the animal's gastrointestinal tract.


In July 2001, the European Union approved potassium diformate as the first alternative to antibiotic growth promoters for pig feed. In April 2003, the European Union passed the guiding regulations again, approving the increase of the maximum safe dosage of commercial potassium diformate in piglets and growing pigs to 1.8%-1.2%. In July 2005, the European Union issued a supplementary committee regulation in time and approved it. Potassium diformate is used as a growth promoter in sow feed.


Oligosaccharides

There are many types of oligosaccharides. The oligosaccharides currently used as feed additives mainly include fructooligosaccharides, galactooligosaccharides, mannose oligosaccharides, soybean oligosaccharides, isomaltose, and xylose oligosaccharides. These oligosaccharides are all short-chain branched sugars, which cannot be decomposed by digestive enzymes secreted by monogastric animals, but they can be digested and utilized by beneficial intestinal microorganisms after entering the digestive tract, selectively promoting bifidobacteria, lactobacilli, and streptococci The proliferation of beneficial bacteria. So, does it mean that it can replace antibiotics to promote the proliferation of beneficial bacteria?


Bacteriostatic: It has no bactericidal effect, but provides nutrients for beneficial bacteria.


Function: The function is relatively one-sided, mainly reflected in intestinal health, which can indirectly improve immunity; it cannot fully replace antibiotics.


Probiotics

As a microecological preparation, the main role of probiotics is to adjust the balance of animal intestinal flora, so it should be mainly used to prevent intestinal diseases. So can it play a practical and feasible alternative value in terms of the role of replacing antibiotics? Function: The main effect is reflected in intestinal health, which has a certain effect on promoting growth and reducing ammonia; effect: poor stability, difficult to control the balance of the flora, increase nutrient consumption, difficult to store, and cause probiotics to be ineffective when used on-site; product standardization insufficient.


Enzyme

Feed enzyme preparations can be roughly divided into two types: digestive enzymes and non-digestive enzymes, which usually play a role at the nutritional level. Such as improving the endogenous enzyme activity in the digestive tract of livestock and poultry, supplementing the deficiency of endogenous enzymes; destroying plant cell walls and improving feed utilization efficiency; eliminating anti-nutritional factors in feed and promoting the digestion and absorption of nutrients.


Antibacterial: no antibacterial effect

Function: The main function is in nutrition, without antibacterial and immunomodulatory functions; it cannot replace antibiotics. The current research on glucose oxidase is not mature and the cost is high.


Plant essential oil

Function: The function is relatively comprehensive, and has the effect of antibacterial and immune regulation.


Insufficiency: Easily volatile, easy to oxidize, and difficult to store (the stability of essential oil products is an important evaluation criterion for their quality).


There are many alternative feed additives, and the best additives are suitable for their own breeding mode. Restricting or banning the use of feed antibiotics has brought severe challenges to the feed and aquaculture industry. The wide application of potassium diformate also provides continuous, healthy and rapid development for animal husbandry in the pst-antibiotic era.

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