How does potassium diformate replace antibiotics?

 Behind the prohibition of feed, breeding technology and cost are both considered. Antibiotics have made an indelible contribution to the animal husbandry industry before the ban. The reason why they have been used is nothing more than the function of promoting growth and preventing diseases. Therefore, the realization of a substitute must start from these two aspects. Potassium diformate is a feed additive that can be matched with corresponding products to meet the corresponding needs in the anti-anti formula and is also an acidulant.


It is still difficult to replace antibiotics with a single product when replacing antibiotics, and a comprehensive alternative plan is needed. Potassium diformate can not only act as an acidifier, but also has anti-fungal effects. If combined with biological feed, it can basically solve the problems caused by the prohibition of resistance to intestinal diseases in poultry and livestock.


From the perspective of antibacterial mechanism, acidifiers mainly have two antibacterial and sterilization mechanisms. One is to release hydrogen ions through dissociation, which reduces the pH of the environment and forms an environment that is unfavorable for the survival of bacteria. The second is that some organic acid molecules can pass through the cell wall and cell membrane, dissociate inside the bacteria, disrupt the bacteria's metabolism, and die. The bactericidal mechanism of organic acids is very different from antibiotics and will not cause resistance.


Potassium diformate contains a large amount of formic acid and does not exist in the form of a salt. Therefore, it has excellent acidification ability. Small molecular organic acids are combined with potassium ions, which can reduce volatility, irritation, and corrosiveness, and solve the safety problem.


As early as in Europe, trials on potassium diformate have been made. Adding more than 10 kg of potassium diformate per ton will not inhibit animal food intake, but instead increase feed intake. The practical application in the country in recent years has also confirmed this point. At the same time, the sustained release of short-chain fatty acids is also achieved. Some small molecular organic acids are released in the stomach and the anterior part of the small intestine, but a certain amount of organic acids reach the back of the small intestine and are released, which has a high buffering capacity.


In the era of anti-resistant breeding, potassium diformate has a good bactericidal and antibacterial effect on Escherichia coli, Salmonella, etc., instead of antibiotics, antibacterial growth promotes lower gastrointestinal PH value, and promotes the growth of beneficial bacteria. Thereby reducing the number of deaths due to bacterial infections. The basic consideration for being a substitute for antibiotics is based on the small molecules of organic acid formic acid and potassium ions, which naturally exist in nature and are eventually metabolized into carbon dioxide and water, which are completely biodegradable.


The cost of feed without resistance will definitely increase, otherwise many companies will replace it. But we should not only focus on economic benefits, but also social benefits. After using potassium diformate to replace antibiotics, the quality of livestock products is guaranteed, and there are fewer antibiotic residues in the environment, which is more beneficial to human health.

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